New NICE guidelines have been published in Feb 2013
They replace previous guidelines
The full guidelines can be found here: http://publications.nice.org.uk/fertility-cg156
Some important changes and new guidance for 2013 includes:
- Do not offer oral ovarian stimulation agents (such as clomifene citrate, anastrozole or letrozole) to women with unexplained infertility.
- Inform women with unexplained infertility that clomifene citrate as a standalone treatment does not increase the chances of a pregnancy or a live birth.
- Offer IVF treatment (see recommendations 184.108.40.206–4) to women with unexplained infertility who have not conceived after 2 years (this can include up to 1 year before their fertility investigations) of regular unprotected sexual intercourse.
- Do not routinely offer intrauterine insemination, either with or without ovarian stimulation
- Offer an earlier referral for specialist consultation to discuss the options for attempting conception, further assessment and appropriate treatment where:
- the woman is aged 36 years or over
- there is a known clinical cause of infertility or a history of predisposing factors for infertility
- Do not use any of the following tests individually to predict any outcome of fertility treatment:
- ovarian volume
- ovarian blood flow
- inhibin B
- oestradiol E2
- For women who are taking clomifene citrate, do not continue treatment for longer than 6 months.
There is also guidance on the number of embryos to transfer for IVF and the number of IVF/ICSI cycles by age.
These points relate to good practice and do not imply that any treatments will be state funded
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